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Research Journal of Pharmacology and Pharmacodynamics
Year : 2010, Volume : 2, Issue : 6
First page : ( 378) Last page : ( 379)
Print ISSN : 0975-4407.

Role of Ficus bengalensis Leaves as a Hepatoprotective on Rifampicin Induced Hepatic Damage in Albino Rats

Gindi Sumalatha1,*, Hawisa Nagiat T.2, Baburao Chandu2, Khagga Mukkanti3

1Hindu College Of Pharmacy, Amaravathi Road, Guntur-522002, Andhrapradesh, India

2College of Pharmacy, Al-Jabal Al-Gharbi University, Al-Zawia, Libya

3Centre for Pharmacy, JNT University, Hyderabad, Andhrapradesh, India

*Corresponding Author: Sumalatha Gindi Hindu College Of Pharmacy, Amaravathi Road, Guntur-522002, Andhrapradesh, India Email: sumacology@gmail.com Phone: 09885098047

Online published on 20 March, 2013.

Abstract

The present investigation explores the hepatoprotective activity of Ficus bengalensis leaf extract in albino rats. The dried leaves of Ficus bengalensis were extracted using ethanol and tested for hepatoprotective activity on albino rats intoxicated with rifampicin (50mg/kg p.o). liver weight, pentobarbitone sleeping time, biochemical parameters was studied. Ethanolic extract of Ficus bengalensis leaf lowered the elevated levels of SGOT, SGPT and serum bilirubin indicating promising anti hepatotoxic activity.

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Keywords

Ficus Bengalensis, Rifampicin, Ethanoloic extract, Hepatoprotective.

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