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Research Journal of Pharmacology and Pharmacodynamics
Year : 2010, Volume : 2, Issue : 4
First page : ( 289) Last page : ( 292)
Print ISSN : 0975-4407.

Hepatoprotective effect of Glinus oppositifolius Linn

Natarajan P.*, Thirupathi A. Thanga, Sekharan T. Raja, Sundar A. S. William Arputha, Arivukkarasu R., Ganesan M.

Department of Pharmacology, Sankaralingam Bhuvaneswari College of Pharmacy, Sivakasi, Tamil Nadu, India

*Corresponding Author: P. Natarajan, Department of Pharmacology, Sankaralingam Bhuvaneswari College of Pharmacy, 3/77-C, Anaikuttam Road, Anaikuttam, Sivakasi-626 130, Tamil Nadu, India. Mobile number: 09842377548 E-mail address: nnatarajan13@yahoo.co.in

Online published on 20 March, 2013.

Abstract

Hepatoprotective effect of a methanolic extract of Glinus oppositifolius Linn root on liver damage induced by Carbon tetrachloride (CCl4) in albino rats. Oral administration of the methanolic extract showed significant protective action made evident by its effect on the level of serum glutamate pyruvate transaminase (SGPT), serum glutamate oxaloacetate transaminase (SGOT), total bilirubin and direct bilirubin. The results of this study showed that treatment with Glinus oppositifolius Linn extracts appears to enhance the recovery from hepatic damage induced by CCl4.

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Keywords

Glinus oppositifolius Linn, Hepatoprotective, serum glutamate pyruvate transaminase (SGPT), serum glutamate oxaloacetate transaminase (SGOT), total bilirubin and direct bilirubin.

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