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Research Journal of Pharmacognosy and Phytochemistry
Year : 2011, Volume : 3, Issue : 1
First page : ( 30) Last page : ( 33)
Print ISSN : 0975-2331. Online ISSN : 0975-4385.

Hair Growth Activity of Trichosanthes dioica R. Leaves

Kumar Nitin, Singh Satyendra,  Manvi, Gupta Rajiv*

Department of Pharmacognosy, Faculty of Pharmacy, Babu Banarasi Das National Institute of Technology and Management Dr. Akhilesh Das Nagar, Faizabad Road, Lucknow- 227 105, U.P (India)

*Corresponding Author: Rajiv Gupta Prof. and Head, Department of Pharmacognosy, Faculty of Pharmacy, Babu Banarasi Das National Institute of Technology and Management, Dr. Akhilesh Das Nagar, Lucknow-227 105 (U.P.) E-mail: rajiv961@rediffmail.com, Mobile: +91 9839278227 Fax no: +91-522-2815187

Online published on 21 March, 2013.

Abstract

Trichosanthes dioica R. (Cucurbitaceae), an important perennial herb found throughout the Asia and is figured high in Indian medicine system for its versatile therapeutic and prophylactic properties. To justify its traditional claim, hair growth activity was performed with ethanol and aqueous extracts on wistar albino rats using minoxidil as standard. The extracts were formulated as 5% ointments and formulations were applied topically on the denuded back of rats. Both formulations exhibited prominent hair growth activity as compared to control group (p<0.05) as well as minoxidil treated group. The number of hairs and hair length were also measured which were more significant for formulations. Formulation having 5% aqueous extract found more potent than other groups. The results of this study revealed the presence of strong hair growth potential in the leaves of Trichosanthes dioica R.

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Keywords

Alopecia, minoxidil, ointment, hair growth.

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