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Research Journal of Pharmacognosy and Phytochemistry
Year : 2010, Volume : 2, Issue : 2
First page : ( 129) Last page : ( 130)
Print ISSN : 0975-2331. Online ISSN : 0975-4385.

Anthelmintic Activity of Spondias pinnata (Linn. F) Kurz

Mondal Sumanta1,*, Dash Gouri Kishore1, Chhetree Rishi Raj2

1Matushree V. B. Manvar College of Pharmacy, Dumiyani, Rajkot District, Gujarat-360 440

2Regional Institute of Pharmaceutical Science and Technology, Agartala, Tripura-799005

*Corresponding Author: Sumanta Mondal, Matushree V. B. Manvar College of Pharmacy, Dumiyani, Rajkot district, Gujarat −360 440. Email: logonchemistry@yahoo.co.in, Contact No.: +91-9375484757

Online published on 21 March, 2013.

Abstract

Present study reports anthelmintic activity of various extracts of the bark of Spondias Pinnata against Indian earthworms Pheritima posthuma. The results revealed that all the tested extracts of Spondias Pinnata bark possess anthelmintic activity in a dose dependant manner. Potency of the test samples was found to be inversely proportional to the time taken for paralysis/death of the worms. The activities were comparable with the reference drug piperazine citrate. Among the tested extracts, the chloroform extract was found to possess promising anthelmintic activity in comparison to other extracts. The present study therefore justifies its use in the folklore remedies as an anthelmintic drug of natural origin.

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Keywords

Anthelmintic, Spondias Pinnata, Pheritima posthuma, Piperazine citrate.

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