Evaluation of Anti Bacterial and Anti Platelet Activity of Ethanolic Leaf Extract of Physalis angulata Jafferi SAH1,*, Sandhya S1, Vinod KR1, Prasad D Narender1, Venkataramana K2 1Nalanda College of Pharmacy, Nalgonda, A.P. 2ASN Pharmacy College, Tenali, A.P. *Corresponding Author: Sandhya S, Department of Pharmacognosy, Nalanda College of Pharmacy, Cherlapally, Nalgonda-508001 Andhra Pradesh, India Mob.no: 09010055004, Email: sanpharm@gmail.com
Online published on 21 March, 2013. Abstract There has always been a closed association between plants and human beings through ancient time and till date. Physalis angulata is an annual herb indigenous to many parts of the tropics, including the Amazon. It can be found on most continents in the tropics, including Africa, Asia, and the Americas. It grows up to 1 m high, bears small, cream-colored flowers, and produces small, light yellowish-orange, edible fruit sometimes referred to as Cutleaf Groundcherry. It is a popular medicine used due to its antiinflammatory effects, anti tumor effects, immunomodulatory effects etc. The present study is to evaluate the anti bacterial and anti platelet activity of the ethanolic leaf extract of Physalis angulata. From the phytochemical screening it was found that the plant is mainly constituted with phenols, steroids and flavonoids.The anti bacterial activity was performed by well diffusion method on various concentrations of the extract. Gentamycin was used as the standard and ethanol as the control. In the antiplatelet activity study, the platelet was induced using adenosine di phosphate. Nephlometer was used to observe the aggregation. It was observed that the ethanolic leaf extract showed pronounced anti platelet activity. But the anti bacterial activity was found to be false positive. Top Keywords Physalis angulata, anti-platelet, anti bacterial, nephlometer. Top |