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Research Journal of Pharmacognosy and Phytochemistry
Year : 2019, Volume : 11, Issue : 4
First page : ( 251) Last page : ( 257)
Print ISSN : 0975-2331. Online ISSN : 0975-4385.
Article DOI : 10.5958/0975-4385.2019.00042.6

A Review on Mucosal Drug Delivery System

Sakshi Mahajan*, Rampal Mandloi, Nikhlesh Birla, Dr. Sujit Pillai

G.R.Y. Institute of Pharmacy, Borawan, Khargone (MP), India

*Corresponding Author E-mail: sakshimahajan2329@gmail.com

Online published on 31 December, 2019.


The main objective of any drug delivery system is to deliver the drug over an specified Period of time, to provide a therapeutic amount of drug at proper site of action. Mucoadhesive drug delivery is one of the important novel drug delivery system. Mucoadhesive dosage form may be designed to prolongs the residence time, rapid onset of action, good bioavailability it also by pass the hepatic first pass metabolism and providing a controlled rate of drug release. There are many routes of mucoadhesive drug delivery system such as buccal route, oral route, Nasal route, ocular route, Gastrointestinal route, vaginal route and rectal route. In the Mucoadhesive drug delivery system the drug comes in contact with the mucous layer and adhere the drug to the epithelial surface of mucous membrane. Mucoadhesion defines the mechanism by which the two material are held together for a specific period of time by interfacial forces. It describes the attractive forces between a biological material and mucous or mucous membrane. This review article gives information about Mucoadhesion Various theories of mucoadhesion, Mechanism of Mucoadhesion, Factors affecting Mucoadhesion, Evaluations and various Mucoadhesive dosage form.



Mucoadhesion, Bioadhesion\ Mucoadhesion Theories, Factors and Evaluations.


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