Investigation of In vitro Anti-cancer property of Adhatoda vasica in Hela, HepG2, MCF-7, MDAMB-231 Cell Lines Nirmala Sankaradoss1,*, Sabapathi P Nadana2, Sudhakar M1, Bathula Naveen3, Sravanthi Y1 1Department of Pharmacognosy, Malla Reddy College of Pharmacy (Affiliated OU), Hyderabad-500014, Telangana, India 2Aizant Drug Research Solutions, Hyderabad-500100, Telangana, India 3School of Pharmaceutical Sciences, VISTAS, Chennai *Corresponding Author E-mail: nirmala.cognosy@gmail.com
Online published on 31 December, 2019. Abstract The anticancer-cytotoxic activities of ethanolic extract of Adhatoda vasica were tested under in-vitro conditions in different cancer cell lines like MCF-7, MDAMB-231, Hela, HepG2 cell lines. The active constituents carbohydrates, steroids, Alkaloids, Tannins, Flavanoids, Saponins, gums and mucilage. The ethanolic extract of Adhatoda vasica showed a good cytotoxic activity (60%, 60%, 85% and 65%) in Hela, HepG2, MCF-7, MDAMB-231 cells at 24 hrs respectively. In this in-vitro studies the normal cells are act as a positive control. The ethanolic extract of Adhatoda vasica shows maximum percentage of 85% after 24 hrs. From this study, it can be concluded that the phytoconstituents of Adhatoda vasica have significant anticancer-cytotoxic activity on Hela, HepG2, MCF-7, MDAMB-231 cells. Top Keywords Investigation of invitro anti-cancer property, Adhatoda vasica. Top |