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Research Journal of Pharmacognosy and Phytochemistry
Year : 2019, Volume : 11, Issue : 2
First page : ( 93) Last page : ( 96)
Print ISSN : 0975-2331. Online ISSN : 0975-4385.
Article DOI : 10.5958/0975-4385.2019.00017.7

Evaluation of Laxative Activity of Panchachurnam: an Ayurvedic Polyherbomineral Formulation

Krishna K.V.V.S.*, Kumar P. Ajay, Akhila P., Samhitha N., Suryaveni P.N.S.G., Kumari P. Harika, Kumar P. Sandeep

Department of Pharmacognosy, Aditya College of Pharmacy, Surampalem, East Godavari District, Andhra Pradesh, India-533 437

*Corresponding Author E-mail: kvvskrishna@rediffmail.com

Online published on 15 May, 2019.

Abstract

Panchachurnam is one of the classical Ayurvedic preparations traditionally used as laxative; it is prepared by mixing equal proportions of powdered Cassia angustifolia Vahl. leaf, Terminalia chebula Retz. fruit, Zingiber officinale Rosc. rhizome, Foeniculum vulgare Mill. fruit and Saindhava lavana. Even though this drug has been used based on traditional knowledge, no scientific work has been done to evaluate its laxative activity. Therefore, the aqueous extract of Panchachurnam was analyzed for its laxative activity using Wistar rats and it has shown significant action at all the tested doses when compared to standard and control, while highest activity exhibited by the higher concentration (400mg/ml) which assures the ethno-medicinal claim. The present study suggested that, Panchachurnam has great potential as a laxative and can be used as an alternative medicine in the treatment of constipation.

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Keywords

Panchachurnam, Constipation, Senna, Laxative activity.

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