Research Journal of Pharmaceutical Dosage Forms and Technology
Year : 2019, Volume : 11, Issue : 4
First page : ( 264) Last page : ( 268)
Print ISSN : 0975-234X. Online ISSN : 0975-4377.
Article DOI : 10.5958/0975-4377.2019.00044.2

Formulation and In Vitro Evaluation of orally Disintegrating Tablets of Amlodipine Besylate

Dr. Reddy Y. Krishna^1,*, Lavanya Gopagoni¹

¹Department of Pharmaceutics, Nalanda College of Pharmacy, Jawaharlal Nehru Technological University, Hyderabad, Telangana

*Corresponding Author E-mail: rajinisuralabs1@gmail.com

Online published on 3 February, 2020.

Abstract

The present study was carried out to Develop Oral Disintegration Tablets of Amlodipine Besylate. Crospovidone, Cros carmellose sodium and Fenugreek were used as Super Disintegrants. The blend of all the Formulations showed good flow properties such as angle of repose, bulk density, tapped density. The prepared tablets were shown good post compression parameters and they passed all the quality control evaluation parameters as per I.P limits. Among all the formulations F4 showed maximum % drug release i.e., 99.44% in 45 min hence it is considered as optimized formulation

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Keywords

Amlodipine Besylate. Crospovidone, Cros carmellose sodium and Fenugreek.

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