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Research Journal of Pharmaceutical Dosage Forms and Technology
Year : 2019, Volume : 11, Issue : 1
First page : ( 15) Last page : ( 18)
Print ISSN : 0975-234X. Online ISSN : 0975-4377.
Article DOI : 10.5958/0975-4377.2019.00003.X

Emetics and Antiemetics: A Review

Rathod Ashok*, Rathod Amol, Tiwari Kundan

Student of Pharmacy, SMBT Institute of Diploma Phrmacy Nandi-Hills Dhamangaon, Nashik

*Corresponding Author E-mail: ashokdrathod999@gmail.com

Online published on 16 March, 2019.

Abstract

Emetics is a complex reflex coordinated by the vomiting centre in the medulla. The afferent and efferent pathaways which cause vomiting are carried by vagus and sympathetic nerves. Chemo-receptor trigger zone is major sensory relay station, present in the lateral border of the area postrema of medulla oblongata. Afferent stimulation like tactile pharyngeal impulses, abryrinthine disturbances, pain, distyension of viscera, psychology factors, increased intracranial pressure, emetic drugs, radiation therapy, electrolyte disturbances, endocrine disturbances, pregnancy etc, cause ‘emesis’ i.e. Vomiting.

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Keywords

Emetic, radiation therapy, CTZ, antiemetics.

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