Users online: 3048    [ij] [ij] [ij] 
Email id

Medicinal Plants - International Journal of Phytomedicines and Related Industries
Year : 2011, Volume : 3, Issue : 3
First page : ( 237) Last page : ( 241)
Print ISSN : 0975-4261. Online ISSN : 0975-6892.
Article DOI : 10.5958/j.0975-4261.3.3.038

Antiprotozoal activity of 2, 3-dihydroxybenzoic acid isolated from the fruit extracts of Flacourtia inermis Roxb.

George Shibumon1, Benny P.J.1,1, Kuriakose Sunny2, George Cincy2, Gopalakrishnan Sarala3

1Department of Zoology, St. Thomas College Palai, Kottayam, Kerala, India

2Research and Post Graduate Department of Chemistry, St. Thomas College Palai, Kottayam, Kerala, India

3Department of Microbiology, St. Pius X College, Rajapuram, Kasaragod, Kerala, India

1 Corresponding author: P.J. Benny e-mail: shibugeorgepala@gmail.com


An attempt has been made to isolate, purify and characterize an antiprotozoal compound from the fruit extract of Flacourtia inermis. Chromatographic technique was used for the isolation and purification of the active principle and the structural elucidation of the compound was done by spectroscopic analysis. Antiprotozoal activity was tested by microscopic count method using fresh water protozoa and rectal ciliates of frog. The study revealed that the purified compound belongs to the phenolic acid class and identified as 2, 3-dihydroxybenzoic acid. Antiprotozoal assay showed that the purified compound at a concentration of 2.5 mg/ml was lethal to the tested organisms. The study can be concluded that the fruit of Flacourtia inermis possesses 2, 3-dihydroxybenzoic acid, which is a powerful antiprotozoal agent against fresh water protozoa and rectal ciliates of frog.



Flacourtia inermis, Loika, 2, 3-dihydroxybenzoic acid, Antiprotozoal, Fresh Water protozoa, Rectal ciliates.


║ Site map ║ Privacy Policy ║ Copyright ║ Terms & Conditions ║ Page Rank Tool
624,806,662 visitor(s) since 30th May, 2005.
All rights reserved. Site designed and maintained by DIVA ENTERPRISES PVT. LTD..
Note: Please use Internet Explorer (6.0 or above). Some functionalities may not work in other browsers.