Serum proteins in goats naturally infected with Theileria lestoquardi Nazifi S., Razavi S.M.1, Esmailnejad Z., Moraveji M.1, Farshneshani F., Rahsepar M., Ghane M.1 Department of Clinical Studies, School of Veterinary Medicine, Shiraz University, Shiraz, 71345-1731, Iran. 1Department of Pathobiology, School of Veterinary Medicine, Shiraz University, Shiraz, 71345-1731, Iran. Abstract Blood samples were collected from jugular vein of 8 clinically and hematologically healthy goats and 28 goats naturally infected with Theileria lestoquardi. The blood smears from infected goats were positive for Theileria lestoquardi and the clinical signs of pyrexia, lymphadenopathy, ocular and nasal discharge, dyspnoea, listlessness, anorexia, weight loss, decline in milk production and finally hypothermia and recumbency with rapid breathing and pulse rate were observed in infected animals. A marked anaemia was noticed in all the infected goats. Serum proteins including albumin, α-globulin, β1 - globulin, β2 - globulin, and γ1 - globulin, were revealed in cellulose acetate electrophoresis. There was a significant increase in serum γ - globulin, a chronic phase protein, and decrease in serum β1 - globulin, in infected goats (P < 0.05). Transferrin as a major protein of serum β1 - globulin is a negative acute phase protein that decreases in inflamatory reactions. Top Keywords Serum protein electrophoresis, Theileriosis, Theileria lestoquardi, Goat, Iran. Top |