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Journal of Innovation in Pharmaceutical Sciences
Year : 2019, Volume : 3, Issue : 1
First page : ( 16) Last page : ( 21)
Online ISSN : 2581-5695.

A Review on Azelaic Acid Emulgel for Acne and Hyperpigmentation

Amrutbhai Halpati Hemangini*, Jaykumar Patel Ankita, Narkhede Sachin B.

Smt. B.N.B Swaminarayan Pharmacy College, M. Pharm, Department of Pharmaceutics, Gujarat, India

*hemanginihalpati0008@gmail.com

Online published on 27 September, 2019.

Abstract

Acne is a very common inflammatory skin disease also known as Pimples. Pimples are commonly found on face, chest, upper back and neck. Propionibacterium and Staphylococcus aureus (S. aureus) are responsible for acne they are mainly present in Sweat gland. Azelaic acid is anti-keratinizing, antibacterial and anti-inflammatory drug. Azelaic Acid is mainly act on cellular protein synthesis in both aerobic and anaerobic bacteria and it reducing the proliferation of Propionibacterium.

Azelaic acid is used to treat acnes as well as Hyperpigmentation and it also reduce inflammation and redness. But Azelaic Acid is Hydrophobic drug low soluble and low permeable so The Aim of present study was to Enhance Permeability and Solubility of Azelaic Acid by Formulating Emulgel For effective treatment of Acne and Hyperpigmentation.

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Keywords

Acne, Hyperpigmentation, Hydrophobic drug, Azelaic Acid, Emulgel.

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