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Journal of Immunology and Immunopathology
Year : 2005, Volume : 7, Issue : 1
First page : ( 1) Last page : ( 7)
Print ISSN : 0972-0561.

Vaccines for control of Salmonellosis

Chauhan Sunil Kumar1,*, Shukla Gunjan2, Vaid Rajesh Kumar3, Sharma Vishweshvar Dutt4

1Department of Hematology (Immunology), Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226014, (UP)

2National Biotechnology Centre, Indian Veterinary Research Institute, Izzatnagar, Barreily, 243122, (UP)

3Division of Goat Health, Central Institute for Research on Goat, Makhdoom, PO Farah, Mathura 281122, (UP)

4Department of Veterinary Microbiology, GB Pant University of Agriculture and Technology, Pantnagar, 263 145, (Uttaranchal), INDIA

*Corresponding author: E-mail: schauhan@sgpgi.ac.in

Abstract

Salmonellosis is a group of ailments caused by the members of genus Salmonella of Enterobacteriaceae family. It is a hazard to food industry and havoc to animal and human health. Although Salmonellosis is mainly associated with gastroenteritis, it also causes substantial economic losses through mortality, decreased production and poor growth. Prevention of Salmonellosis by implementation of hygienic measures is difficult and antibiotic treatment of infection can be problematic due to the recent emergence of multi-drug-resistant Salmonella strains. Vaccination is the only effective tool for the prevention of Salmonella infections. The currently available vaccines against salmonellosis can be broadly divided in to three major classes namely killed, live and subunit vaccine. Inspite of tremendous amount of work done on immunoprophylaxis against salmonellosis, not much has been achieved. Till date no single vaccine is available that can protect against ever increasing serovars of Salmonella. In this review, we attempt to summarise the progress that has been made for the development of suitable vaccines against salmonellosis.

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Key Words

Salmonella, Immunoprophylaxis, killed vaccines, live vaccines, subunit vaccines.

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