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Journal of Immunology and Immunopathology
Year : 2003, Volume : 5, Issue : 1
First page : ( 47) Last page : ( 50)
Print ISSN : 0972-0561.

Effect of Neem (Azadirachta indica) leaf extract administration on immune responses of broiler chickens

Sridhar Renu1, Rakha N.K.1, Gera Sandeep2, Mishra S.K.3

1Department of Clinical Medicine, Ethics and Jurisprudence, CCS HAU, Hisar-125 004, (Haryana), INDIA.

2Department of Veterinary Biochemistry, CCS HAU, Hisar-125 004, (Haryana), INDIA.

3Department of Veterinary Pathology, CCS HAU, Hisar-125 004, (Haryana), INDIA.


Effect of Neem leaf extract administration was studied on cell mediated and humoral immune responses of broiler chickens. Ten percent Neem leaf extract was prepared following boiling of 100 g dried Neem leaves in one litre drinking water for treated chicks. Administration of Neem leaf extract enhanced cell mediated immune response as observed by DTH in term of increased skin thickness to 2,4-dinitro-chlorobenzene in skin contact sensitivity test and enhanced humoral immune response against NOV antigen as detected by indirect ELISA. The present findings indicate that Neem leaf extract have an immunopotentiating effect.


Key words

Neem, Azadirachta indica, Immune response, Immunomodulation.


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