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Journal of Dental and Orofacial Research
Year : 2018, Volume : 14, Issue : 1
First page : ( 49) Last page : ( 54)
Print ISSN : 2347-2588. Online ISSN : 2347-2758.

Vaccine for Dental Caries-An Imminent Target

Abraham M.1,*, Shwetha K. N.2, Vanishri H.C.3, Roopa R.S.4, Dominic A.5, Sowmya S.V.6

1Post Graduate Student, Department of Oral Pathology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bengaluru-560054

2Tutor, Department of Oral Pathology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bengaluru-560054

3Assitant Professor, Department of Oral Pathology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bengaluru-560054

4Professor and Head, Department of Oral Pathology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bengaluru-560054

5Assitant Professor, Department of Oral Pathology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bengaluru-560054

6Associate Professor, Department of Oral Pathology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bengaluru-560054

*Corresponding Author E-Mail: marinabraham09@gmail.com

Online published on 18 January, 2019.

Abstract

Cariosity is an inevitable microbial malady primarily induced by pathogens like streptococcus mutans. The hard tissue of the oral cavity is affected by the host agent and environment. Time factor plays an important role for development and progression of dental caries that is observed in all parts of the world with no predilection to gender, socioeconomic strata and age group. However dental caries has overcome the phase of being unrestrained with various scientific advancements. Numerous clinical trials affirm that tooth decay can be interrupted by approaches such as to sustain adequate levels of salivary antibodies and to establish immune memory for greater span. Efforts are being carried about to achieve a definite route of administration and to evaluate the safety of vaccines to overcome the likely uncertainty.

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Keywords

Animal Model, Dental Caries, Immune Memory, Teeth, Salivary Antibodies.

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