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Journal of Animal Research
Year : 2011, Volume : 1, Issue : 1
First page : ( 51) Last page : ( 55)
Print ISSN : 2249–5290.

Enzymatic and haematological studies on efficacy of some hepatoprotective herbal and non-herbal formulations

Sharma R.K.1,*, Sharma Varsha2, Trivedi Piyush3Vice Chancellor

College of Veterinary Science and Animal Husbandry, Jabalpur, Madhya Pradesh, India

Present Address: 1Department of Veterinary Pharmacology and Toxicology

2 Department of Veterinary Microbiology

3 RGPV, Bhopal, Madhya Pradesh

* Corressponding Author: Email: drrajeshsharma04@yahoo.co.uk

Online published on 23 January, 2012.

Received:  13  August,  2011; Accepted:  5  September,  2011.

Abstract

Hepato-toxicity was induced experimentally in 162 rats with single dose of paracetamol @ 500 mg/kg B.Wt. to observe the enzymatic and haematological efficiency of some hepatoprotective formulations (F) of herbal and nonherbal nature. Study of Serum Aspartate Aminotransferase (AST), Serum-L-Alanine Aminotransferase (ALT) and Serum Alkaline Phosphatase (SAP), TLC, DLC, TEC, Hb, PCV etc. were done. The results indicated that hepatoprotective herbal formulations employed in present study, were having better effect than nonherbal formulations.

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Keywords

Hepato-toxicity, Paracetamol, Hepatoprotective, Serum Aspartate Aminotransferase, Serum Alkaline Phosphatase.

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