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Year : 2022, Volume : 15, Issue : 1and2
First page : ( 9) Last page : ( 13)
Print ISSN : 0973-8940. Online ISSN : 2454-762X. Published online : 2022  15.
Article DOI : 10.5958/2454-762X.2022.00002.6

Overview of Antimicrobial Compounds Produced from Bacteria

Agarwal Shruti, Patel Sunny, Rai Pankaj Kumar*

Department of Biotechnology, Invertis University, Bareilly-243123, Uttar Pradesh, India

*Corresponding author email id: pankaj.r@invertis.org; pankajraibhu@gmail.com

Online published on 15 September, 2022.

Received:  21  December,  2021; Accepted:  23  ,  2022.


Every year more than 10 million lives are lost due to antimicrobial-resistant infections. Therefore, the development of antimicrobial agents has become a necessity. Natural products are being used as therapeutic agents. Antimicrobial beings are one of the most compelling molecules. Microorganisms produce bioactive compounds with antimicrobial and cytotoxic bioactivity. Fungi and bacteria are mostly used as novel antimicrobial agents. In the years 1940 & 1950 marine bacteria were shown to produce antimicrobial compounds. The first marine antibacterials were identified in the year 1960, and in the year 1970 their antibiotic properties has been reported. The majority of identified compounds were isolated from Actinobacteria & Bacilli. The interesting fact is that the molecules that were active against gram-negative were isolated from Bacilli. It is estimated at least 4-5% of the genome of any strain of the B. subtilus group is devoted to antimicrobial compounds (AMCs) production.



Antimicrobial compound, Microorganisms, Antibacterial, Natural products.


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