Using gas chromatography-mass spectrum and Ft-IR techniques for analysis of methanolic extract of Digitalis purpurea and investigation of its anti-microbial activity Kadhim Shaymaa Abdul Hadi1, Hamza Lena Fadhil2, Hameed Imad Hadi3,* 1Department of Biology, College of Science, University of Babylon, Hillah City, Iraq 2College of Pharmacy, University of Babylon, Hillah City, Iraq 3Biomedical Science Department, University of Babylon, College of Nursing, Hillah City, Iraq *Corresponding author: Imad Hadi Hameed, [Biomedical Science Department, University of Babylon, College of Nursing, Hillah city, Iraq; Phone number: 009647716150716; E-mail: imad_dna@yahoo.com
Online published on 21 September, 2018. Abstract Digitalis purpurea (foxglove, common foxglove, purple foxglove or lady’s glove) is a species of flowering plant in the plantain family Plantaginaceae. The objective of this study were analysis of the secondary metabolite products and investigation of its anti-microbial Activity. GC-MS analysis of methanolic extract of Digitalis purpurea revealed the existence of the 4H-benzopyran-4-one, 6, 7-dimethoxy-3-phenyl, Eucalyptol, 7, 8-Dihydro-7-methyl-2-phenyl-6-p-tosylamino-pyrido[4, 3-d], Octanoic acid, 6-hydroxy-8-methoxy-, ε-lactone, 1, 3-Dioxolane, 2, 2-dimethyl-4-[[(2-methylhexadecyl)oxy]meth, Bicyclo[2.2.1]heptane2, 5-diol, 1, 7, 7-trimethyl-, (2-endo, 5-ex, 1-Hydroxy-4, 4-dimethylcyclohexanecarbonitrile, Bicyclo[3.1.1] hept-2-en-4-ol, 2, 6, 6-trimethyl-, acetate, 12, 15-Octadecadiynoic acid, methyl ester, 2-Cyclohexene-1 methanol, 2, 6, 6-trimethyl, 1-(Cyclopropyl-nitro-methyl)-cyclopentanol, 11-Oxa-dispiro[4.0.4.1]undecan1-ol, Muramic acid, 10-Chlorotricyclo[4.2.1.1(2, 5)]deca-3, 7-dien-9-ol, D-Fructose, diethyl mercaptal, pentaacetate, 10-Octadecenoic acid, methyl ester, 9, 12-Octadecadienoic acid (Z, Z), 3h-Naphtho[2, 3-b] furan-2-one, 4-hydroxy-4a, 5-dimethyl-3, 9, 12, 15-Octadecatrienoic acid, 2-phenyl-1, 3-dioxan-5-yl ester, and α-Tocopheryl acetate. Digitalis purpurea has maximum zone against Streptococcus faecalis (4.671±0.21). Top Keywords Digitalis purpurea, GC-MS, Bioactive, Natural compounds. Top |