Isolation and Characterization of Active Compound from Stem Bark of Streblus asper
Kandali R1, Konwar B K2
1Department of Biochemistry and Agril. Chemistry, B N College of Agriculture, Assam Agricultural University, Biswanath Chariali, Assam-784176, India
2Vice Chancellor, Nagaland University (central), Lumami, Nagaland, India
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Online published on 11 January, 2013.
Streblus asper is widely used in folk medicine in the north eastern region of India. The methanol extract of the stem bark of the plant was partitioned sequentially with petroleum ether, ethyl acetate, chloroform and butanol and the antimicrobial activity of the different extracts was determined. The antimicrobial activity was found in the petroleum ether extract which afforded SA2 as the major bioactive compound showing highest antimicrobial activity against Bacillus subtilis followed by Staphylococcus aureus, Candida albicans and Escherichia coli. On the basis of IR, HRFABMS, 1H NMR, 13C NMR spectroscopic data, the structure of the compound was determined to be Lup-20(29)-en-3 β-01.
Streblus asper, stem bark, antimicrobial activity.