Bioproduction of Lactic Acid Exposed to Metronidazole Shivankari1, Singh Shalini2, Singh S. P.1,* 1Department of Chemistry, Magadh University, Bodh-Gaya 2Department of Chemistry, Govt. Autonomous Model Science College, Bilaspur, (C.G.) *Corresponding Author Email: profspsingh786@gmail.com
Abstract The efficacy of metronidazole on bioproduction of lactic acid by some lactic acid producing bacteria such as Lactobacillus jugrti NCIM- 2367, Lactobacillus lactis NCIM-2369, Lactobacillus plantarum NCIM-2373, Lactobacillus brevis NCIM-2436 and Lactobacillus delbrueckii NCIM-2025 has been studied. The bacterial strain Lactobacillus delbrueckii NCIM-2025 has been found quite effective and useful for maximum bioproduction of lactic acid, i.e,; 11.253 g/100 ml of lactic acid which is 17.096% higher in comparison to control fermentor flasks, i.e,; 9.610 g/100ml at 7.0×10 M molar concentration of metronidazole mutagene. It has been found that bioproduction of lactic acid in the presence of metronidazole at optimum molar concentration, i.e; at 7.0×10 M attains its best activity when 24% (w/v) molasses solution is allowed to ferment for 5 days of optimum incubation period, at 38°C temperature by maintaining the pH value of the fermentation medium at 5.9 along with other nutritional ingredients required by the lactic acid bacteria. Top Keywords: Lactic acid fermentation, Metronidazole, Molasses, Lactobacillus delbrueckii NCIM-2025, pH, Temperature and incubation period.. Top |