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Bio Science Research Bulletin
Year : 2016, Volume : 32, Issue : 1and2
First page : ( 9) Last page : ( 15)
Print ISSN : 0970-0889. Online ISSN : 2320-3161.
Article DOI : 10.5958/2320-3161.2016.00002.X

Photochemical Activation of Polyvinyl Chloride for Immobilization of Invertase

Naqvi Azmi1,*, Sharma Dinesh C.1, Nahar Pradip3, Parween Shahila2

1Department of Zoology, Km. Mayawati Government Girls P.G. College, Badalpur, Gautam Buddha Nagar, Uttar Pradesh, 203207

2Department Innovative Diagnostics, CSIR-Institute of Genomics and Integrative Biology, Mall Road, Delhi-110 007, India

3New Idea Lab, C-202, Ramkrishnan Cooperative Group Housing Society, Plot-12, Sector 23, Dwarka, New Delhi, 110077, India

*Corresponding author. Email: azmi.naqvi@rediffmail.com

Online published on 21 January, 2017.

Abstract

Herein, we describe a method for immobilization of biomolecules onto polyvinyl chloride activated by 1-fluoro-2-nitro-4azidobenzene (FNAB) for a photochemical reaction. Immobilizing biomolecules onto the polyvinyl chloride surface were either very tedious to carry out or they require some specialized conditions and techniques for immobilization. Herein, we report a mild procedure for a covalent immobilization of enzymes using FNAB. HRP (Horse Radish Peroxidase) and invertase were chosen for demonstrating its efficacy onto activated polyvinyl chloride.

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Keywords

1-fluoro-2-nitro-4-azidobenzene, Immobilization, Horse Radish Peroxidase, invertase, polyvinyl chloride.

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