In vivo and In vitro hepatoprotective studies of various extracts of Aphnamixis polystatchya Valan M.F.1, Venkataraman R.2, Britto A. John de3 Department of Chemistry, Sakthi Engineering College, Thiruninravur – 602 024, Tamil Nadu, India 1Lecturer, Department of Chemistry, Sri Paramakalyani College, Alwarkuruchi, Thirunelveli 2Reader, Department of Chemistry, Sri Paramakalyani College, Alwarkuruchi, Thirunelveli 3Reader, Department of Biotechnology and Plant Biology, St Xavier’s College (Autonomous), Thirunelveli (TN) Online published on 22 February, 2013. Abstract The Alcoholic extract of bark and leaf of Aphanamixis polystachya (Wall) Parker for its anti hepatotoxic activity against Isonizid (INH) and Rifampicin (RIF) induced hepatic damage in rats. The activity was evaluated by using biochemical parameters such as total Bilirubin, total protein, Alkaline phosphatase (ALP), Asiartate Transaminase (AST), Alanine Transaminase (ALT), glutamate transpeptidase (GGTP). The histopathalogical changes of liver sample were compared with respective control. The extract showed remarkable hepatoprotective effect. Top Keywords Aphanamixis polystachya, Hepatoprotective, INH & RIF, Biochemical parameters, Histopathological studies. Top |