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Asian Journal of Research in Pharmaceutical Science
Year : 2019, Volume : 9, Issue : 4
First page : ( 270) Last page : ( 272)
Print ISSN : 2231-5640. Online ISSN : 2231-5659.
Article DOI : 10.5958/2231-5659.2019.00042.0

A Case Report on Hepatic Encephalopathy in Chronic Liver Disease with Portal Hypertension

Thokada Sai Saran*

Department of Pharmacy Practice, Vignan Institute of Pharmaceutical Technology, Duvvada, Visakhapatnam

*Corresponding Author E-mail: tsaisaran11@gmail.com

Online published on 3 January, 2020.


Hepatic Encephalopathy (HE) is broadly defined as a reversible and metabolically induces neuropsychiatric complication, often associated with cirrhosis. Manifestations mainly occur due to the accumulations of toxic substances in the liver, which are actively removed by the liver. Chronic liver disease in the clinical context is a disease process of the liver that involves a process of progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis. The present case report deals with the study of 42 years old male who was admitted with chief complaints of diarrheal illness, abdominal distension and fever. It was also accompanied by pedal swelling. Upon physical examination, dilated veins were found on the anterior abdominal wall from below upwards. Laboratory tests performed included complete sodium and potassium (serum), blood count, urea and creatinine tests, liver function tests and also specialized tests such as CT scan and ultra sound were performed where hepatic encephalopathy in chronic liver disease with portal hypertension was confirmed.



Hepatic encephalopathy, chronic liver disease, decompensation, acute diarrheal illness, portal hypertension.


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