[ij] [ij] [ij] 
Email id

Asian Journal of Research in Pharmaceutical Science
Year : 2016, Volume : 6, Issue : 3
First page : ( 198) Last page : ( 202)
Print ISSN : 2231-5640. Online ISSN : 2231-5659.
Article DOI : 10.5958/2231-5659.2016.00023.0

Synthesis and Evaluating Anti-Inflammatory, Antibacterial activity of substituted benzylidene Thiazolidinediones

Patil Sushil D.*, Dr. Sharma Ashish Kumar

Department of Pharmaceutical Chemistry, NIMS University, Shobha Nagar, Delhi Highway, Jaipur, 303121, Rajasthan

*Corresponding Author E-mail: sushilpharma@rediffmail.com

Online published on 18 October, 2016.


This compound we synthesize by a Knoevenagel condensation of 4-aminobenzaldehyde with compound (I) in presence of sodium acetate, but this compound do not comply with the primary aromatic amine test like nitrous acid test and carbylamine test as well as H1 NMR spectra, in this reaction the amine group of benzaldehyde was further reacted another molecules of aldehydes. We modified the process and synthesized compound (Ia), the nitro group of compound Ia was converted in amino group by reduction.



Thiazolidinedione, benzaledhyde, Schiff base.


║ Site map ║ Privacy Policy ║ Copyright ║ Terms & Conditions ║ Page Rank Tool
755,258,576 visitor(s) since 30th May, 2005.
All rights reserved. Site designed and maintained by DIVA ENTERPRISES PVT. LTD..
Note: Please use Internet Explorer (6.0 or above). Some functionalities may not work in other browsers.