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Asian Journal of Research in Pharmaceutical Science
Year : 2013, Volume : 3, Issue : 4
First page : ( 170) Last page : ( 177)
Print ISSN : 2231-5640. Online ISSN : 2231-5659.

An Overview on Versatile Molecule: 1,3-Thiazines

Jupudi Srikanth1,*, Padmini K.1, Preethi P. Jaya1, Bharadwaj P.V.P. Deepak2, Rao P. Vengal2

1Department of Pharmaceutical Chemistry, Sree Vidyanikethan College of Pharmacy, A. Rangampet, Tirupati, Andhra Pradesh, India

2Department of Pharmacology, Sree Vidyanikethan College of Pharmacy, A. Rangampet, Tirupati, Andhra Pradesh, India

*Corresponding Author E-mail: srikanthjupudi@gmail.com

Online published on 5 June, 2014.

Abstract

1,3-Thiazines are six membered heterocyclic rings with N-C-S linkage which have promising pharmacological activities which have drawn the attention of scientists. It is present in the fused form with β-lactam ring in major class of antibiotics like cephalosporins which shows the prevalence of 1,3-thiazines. The current review focuses the significance of 1,3-thiazine derivatives as potential pharmacological moiety and future of these derivatives in the field of drug research. Some of the pharmacological activities are briefly summarized and the tables indicate the compounds with their substituted functional groups.

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Keywords

1,3-thiazines, N-C-S linkage, β-lactam ring, Cephalosporins, Drug research.

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