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Asian Journal of Research in Pharmaceutical Science
Year : 2020, Volume : 10, Issue : 3
First page : ( 149) Last page : ( 152)
Print ISSN : 2231-5640. Online ISSN : 2231-5659.
Article DOI : 10.5958/2231-5659.2020.00028.4

Preparation and evaluation of antibacterial herbal mouthwash against oral pathogens

Yadav Akshay R.*, Mohite Shrinivas K., Magdum Chandrakant S.

Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon, Maharashtra, India-415404

*Corresponding Author E-mail: akshayyadav24197@gmail.com

Online published on 16 September, 2020.


The present research is aimed to formulate and evaluating herbal mouthwash and evaluating its efficacy against microbial oral cavity load. Due to its physicochemical properties and antimicrobial activity, prepared mouthwash was further evaluated. Malvastrum coromandelianum and Neem extracts and the polyherbal mouth rinse demonstrated good sensitivity to micro-organisms such as E. coli and S. aureus. Natural herbs such as malvastrum coromandelianum, Neem and fennel and many others are used as single or in combination have been scientifically proven to be safe and effective medicine against oral health problems such as bleeding gums, halitosis, mouth ulcers, and preventing tooth decay. Clove is most commonly applied directly to the gums for toothache, pain control during work, and other dental-related issues. We have developed a mouthwash with some common food materials and herbs and which can replace costly chemicals like alcohol, coloring agents and preservatives making our mouthwash economically more viable than commercial mouthwash. The anti-inflammatory and anti-infectious properties of neem make it a powerful treatment for gum disease. The results of this study indicate that the existence of compounds such as glycosides, terpenoids, flavanoids and saponins that can be responsible for the antibacterial efficacy of extracts and polyherbal mouthwash rinse against these microorganisms that are known to be mostly responsible for oral cavity bacterial infection.



Herbal mouthwash, Malvastrum coromandelianum, Antibacterial efficacy.


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