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Asian Journal of Research in Pharmaceutical Science
Year : 2020, Volume : 10, Issue : 2
First page : ( 79) Last page : ( 84)
Print ISSN : 2231-5640. Online ISSN : 2231-5659.
Article DOI : 10.5958/2231-5659.2020.00015.6

Analysis of Osteoporosis risk factors in Menopausal women's of Algeria population

Zerzour Aicha1, Haddig Nour El-Houda1, Derouiche Samir1,2,*

1Department of Cellular and Molecular Biology, Faculty of Natural Sciences and Life, University of El Oued, El-Oued, 39000, Algeria

2Laboratory of Biodiversity and Application of Biotechnology in the Agricultural Field

*Corresponding Author E-mail: dersamebio@gmail.com

Online published on 3 June, 2020.


Background and Purpose

This study aim at evaluating some risk factors in women with osteoporosis disease (OP) in Guemar (El Oued, Algeria) region

Materials and Methods

The study was based on 241 voluntary individuals divided into menopausal healthy women reserved as a control with average age of 49.23±3.73 years old and osteoporosis menopausal women (patients) with average age of 49.97±3.21 years old; their origin covers the whole Guemar (El Oued, Algeria) region. Risk of certain socio-clinical factors was estimated by the determination of the value of Odd Ratio (OR)


Our study showed a high association between clinical factors such as thyroid problems, hormonal alternatives, menstrual perturbations and vitamin D deficiency before menopause (OR = 6.682, 5.688, 5.516; p ≤ 0.05) with Osteoporosis disease among the menopausal women respectively. We showedalso that the bone problems before menopause, family historywere the most dangerous risk factor, (OR = 65.646; p = 0.000 and OR= 41.152; p=0.000) respectively, whilemilk, fish diet, legumes, fresh vegetables and fruits, sunshine exposure, walking sport and menopause after 50 years (OR ranging from 0, 029 to 0.463, p <0.038) are important protective factors against this disease


In conclusion lifestyle is a contributing factor in osteoporosis attainment in the region of Guemar (El Oued, Algeria), which requires high sensitivity to modify these behaviorsto limit the progression of the disease in the study region.



Osteoporosis, Risk Factors, Odds Ratio, Menopause, Guemar.


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