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Asian Journal of Research in Chemistry
Year : 2016, Volume : 9, Issue : 3
First page : ( 107) Last page : ( 112)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.
Article DOI : 10.5958/0974-4150.2016.00019.5

Synthesis and Biological Evaluation of Novel 1, 3, 4-Thiadiazole Heterocyclic Derivatives as Novel Anti-Microbial Agents

Dr. Thriveni P., M. Krishna Hari*, Murali K., Sekhar T.

Department of Chemistry, Vikrama Simhapuri University, Nellore-524003, A.P., India

*Corresponding Author E-mail: hari12science@gmail.com

Online published on 23 May, 2016.

Abstract

Heterocyclic compounds are commonly used Scaffolds on which pharmacophores are arranged to provide potent and selective drugs. This is especially true for five-membered ring heterocyclic compounds, which serve as the core components of many substances that possess a wide range of interesting biological activities. New series of 1, 3, 4-Thiadiazole derivatives were synthesized From Benzyl Isocynate and Acid hydrazide, by using P-TsCl in NMP, The Novel Derivatives have been screened for their antimicrobial activity.

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Keywords

1, 3, 4-Thiadiazoles, Synthesis, Anti-bacterial activity and Anti-Fungal activity.

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