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Asian Journal of Research in Chemistry
Year : 2016, Volume : 9, Issue : 3
First page : ( 107) Last page : ( 112)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.
Article DOI : 10.5958/0974-4150.2016.00019.5

Synthesis and Biological Evaluation of Novel 1, 3, 4-Thiadiazole Heterocyclic Derivatives as Novel Anti-Microbial Agents

Dr. Thriveni P., M. Krishna Hari*, Murali K., Sekhar T.

Department of Chemistry, Vikrama Simhapuri University, Nellore-524003, A.P., India

*Corresponding Author E-mail: hari12science@gmail.com

Online published on 23 May, 2016.


Heterocyclic compounds are commonly used Scaffolds on which pharmacophores are arranged to provide potent and selective drugs. This is especially true for five-membered ring heterocyclic compounds, which serve as the core components of many substances that possess a wide range of interesting biological activities. New series of 1, 3, 4-Thiadiazole derivatives were synthesized From Benzyl Isocynate and Acid hydrazide, by using P-TsCl in NMP, The Novel Derivatives have been screened for their antimicrobial activity.



1, 3, 4-Thiadiazoles, Synthesis, Anti-bacterial activity and Anti-Fungal activity.


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