Microwave assisted synthesis, spectral studies and biological evaluation of some benzimidazole derivatives. Al-Shamkhani Zeki A. Naser* Dept. of Chemistry, College of Science, University of Basrah, Basrah, Iraq *Corresponding Author E-mail: alshamkhani.zeki@yahoo.com
Online published on 9 March, 2017. Abstract Benzimidazole (A) was synthesis by reaction of phenylenediamine with 4-p-amino benzaldehyde and then Schiff base synthesis by reaction amino benzimidazole with terphthaldehyde. Azetidinone (C) and Thaizolidinone (D) were also synthesized by reaction benzimidazole Schiff base with acetyl chloride and mercpto acetic acid respectively. These compounds have been synthesis by microwave irridation and characterized by M.P., TLC, CHN, UV, FT-IR, 1HNMR, and 13CNMR. The biological screening data of the synthesized compounds were also studied. Top Keywords Microwave, Benzimidazole, Schiff base, Azetidinone, Thaizolidinone, Anti-bacterial. Top |