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Asian Journal of Research in Chemistry
Year : 2015, Volume : 8, Issue : 3
First page : ( 165) Last page : ( 169)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.
Article DOI : 10.5958/0974-4150.2015.00029.2

Synthesis and evaluation of 5,6-dinitro and 2-dialkylaminosubstituted benzimidazolesderivatives as potential antimicrobial agents

Maske Pratik P.1, Nalavade Sunil1, Malavi Shobhraj B.2, Jawarkar Somkant V.3, Ardad Rameshwar M.4, Lokapure Sachin G.4,*

1Gulabrao Patil College of Pharmacy, Miraj

2SBMSPM's College of Pharmacy, Peth Vadagaon, Kolhapur

3S.D. Patil Institute of Pharmacy, Urun, Islampur

4Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli

*Corresponding Author E-mail: sachinlokapure@yahoo.in

Online published on 2 May, 2015.

Abstract

New series of 5,6-dinitro and 2-dialkylamino substituted benzimidazoles A6–10 were synthesized by the Schiff's Base method. Synthesized compounds A6–10 were confirmed by IR, 1H NMR, Mass and elemental analysis andfurther screened for antimicrobial activity.

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Keywords

5, 6-dinitro, Schiff's Base, Antibacterial activity, Antifungal activity.

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