The synthesis, characterization and biological activity investigation of mixed ligand Coordinated Ni(II) Complexes Md. Bashar Abul, Md. Mannan Abdul, Md. Hossen Faruk, Md. Islam M. Saidul, Md. Kudrat-E-Zahan* Department of Chemistry, Faculty of Science, Rajshahi University, Rajshahi-6205, Bangladesh *Corresponding Author E-mail: kudrat.chem@ru.ac.bd
Abstract The synthesis and investigation of the electronic properties of Ni(II) metal complexes with amino acids and heterocyclic amines have been has been carried out on the basis of metal estimation, conductivity and magnetic measurements, infrared spectra and electronic spectra studies. The complexes were of [M(X)L] where M = Ni(II) and X= deprotonated amino acids as a primary ligand, such as glycine and cysteine; L= heterocyclic amines as a secondary ligand, such as quinoline, isoquinoline pyridine, 1,10-phenanthroline, 8-hydroxyquinoline, 2-picoline, 4-picoline. Antibacterial activity of the complexes has been examined against six (gram positive and gram negative) pathogenic bacteria by disc diffusion method and compared with that of standard antibiotic (Kanamycin). The complexes have been found to have moderate to strong antibacterial activity against the tested bacteria. Top Keywords Transition metal Ni(II) complex, spectra, Antimicrobial activity, Heterocyclic amines, Amino acids. Top |