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Asian Journal of Research in Chemistry
Year : 2011, Volume : 4, Issue : 3
First page : ( 335) Last page : ( 338)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.

Oxindoles and Their Pharmaceutical Significance-an Overview

Rudrangi Shashi Ravi Suman1,*, Bontha Vijaya Kumar2, Manda Venkata Reddy3a,3b, Bethi Srinivas4

1Department of Pharmaceutical Sciences, School of Sciences, University of Greenwich, Chatham Maritime, Kent, United Kingdom, ME4 4TB

2Department of Pharmaceutics, Jangaon Institute of Pharmaceutical Sciences, Kakatiya University, Yeshwanthapur, Jangaon-506167, India

3aFormer Director, Drugs Control Administration, Andhra Pradesh

3bDirector, Sree Dattha Institute of Pharmacy, Sheriguda, Ibrahimpatnam-501510, India

4Department of Medicinal Chemistry, Talla Padamavathi College of Pharmacy, Urus, Kareemabad-506002, India

*Corresponding Author E-mail: suman_rudrangijips@yahoo.com

Online published on 6 March, 2013.

Abstract

Oxindoles are credited to have a wide range of applications and are reported to exhibit an extensive range of biological effects which include the antiviral, antifungal, antibacterial, antiproliferative, anticancer, anti-inflammatory antihypertensive and the anticonvulsant activities. The chemistry of oxindoles is very interesting and the biological activity of the oxindoles and their derivatives has made them very important in synthetic organic and medicinal chemistry. This review provides insight into various applications of oxindoles and their derivatives to date.

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Keywords

Oxindoles, Oxindole derivatives, Applications, Biological Activity.

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