Oxindoles and Their Pharmaceutical Significance-an Overview Rudrangi Shashi Ravi Suman1,*, Bontha Vijaya Kumar2, Manda Venkata Reddy3a,3b, Bethi Srinivas4 1Department of Pharmaceutical Sciences, School of Sciences, University of Greenwich, Chatham Maritime, Kent, United Kingdom, ME4 4TB 2Department of Pharmaceutics, Jangaon Institute of Pharmaceutical Sciences, Kakatiya University, Yeshwanthapur, Jangaon-506167, India 3aFormer Director, Drugs Control Administration, Andhra Pradesh 3bDirector, Sree Dattha Institute of Pharmacy, Sheriguda, Ibrahimpatnam-501510, India 4Department of Medicinal Chemistry, Talla Padamavathi College of Pharmacy, Urus, Kareemabad-506002, India *Corresponding Author E-mail: suman_rudrangijips@yahoo.com
Online published on 6 March, 2013. Abstract Oxindoles are credited to have a wide range of applications and are reported to exhibit an extensive range of biological effects which include the antiviral, antifungal, antibacterial, antiproliferative, anticancer, anti-inflammatory antihypertensive and the anticonvulsant activities. The chemistry of oxindoles is very interesting and the biological activity of the oxindoles and their derivatives has made them very important in synthetic organic and medicinal chemistry. This review provides insight into various applications of oxindoles and their derivatives to date. Top Keywords Oxindoles, Oxindole derivatives, Applications, Biological Activity. Top |