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Insilico Molecular docking analysis in Maestro Software Galande Avanti K.1,*, Rohane Sachin H.1 1Department of Pharmacy, Yashoda Technical Campus, Satara- 415015, India. *Corresponding Author E-mail:avantigalande7938@gmail.com
Abstract The maestro is the scientific leader in developing state-of-the-art chemical stimulation software for use in pharmaceutical, biotechnology, and, materials science research. Maestro is the portal to all of maestros computational technology-far more than just a user interface, Maestro also helps researches organize and analyz data. Maestro is the culmination of years of research and development. by working closely to be the user environment that is both intuitive and allows our users to get work done efficiently. The typical bacteria form a biofilm which barrier for antibiotics and other harmful substances. The capacity of phages to penetrate that. In the study, we showed that Galloflavin and Ellagic acid increased SIRT6 activity and decreased the expression of SIRT6 associated proteins involved in cancer development. Taken together, Galloflavin and Ellagic acid targeting SIRT6 activity may provide a new insight in the development of anti-cancer therapy. As cetuximab exhibits several anticancer mechanisms, in vivo studies are needed to explore and confirm the effects of combining osimertinib with cetuximab in the L858R/T790M/L792H-mutant pattern. Top Keywords Molecular docking, Drug discovery, Maestro software. Top | | | |
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