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Year : 2020, Volume : 13, Issue : 6
First page : ( 489) Last page : ( 493)
Print ISSN : 0974-4169. Online ISSN : 0974-4150. Published online : 2020  15.
Article DOI : 10.5958/0974-4150.2020.00086.3

The effect of Chronic Tobacco smoking on Atherogenic index and Cardiovascular diseases risk in El-Oued (Algeria) Men

Sara Chetehouna1, Ouidad Atoussi1, Islam Boulaares1, Yousra Guemari Imane1, Samir Derouiche1,2

1Department of Cellular and Molecular Biology, Faculty of Natural and Life Sciences, University of Echahid Hamma Lakhdar El Oued, El Oued39000, Algeria.

2Laboratory of Biodiversity and Application of Biotechnology in the Agricultural Field, University of El Oued, El-Oued39000, Algeria.

Received:  07  ,  2020; :  18  ,  2020; Accepted:  08  October,  2020.


Our study aimed to evaluate the effect of cigarette consumption on lipid profile, blood pressure and biochemical biomarkers of cardiovascular diseases in smoker’s men. The experimentation is carried out on 22 voluntary individuals were divided into two groups; the first group of healthy individuals (controls) and the second group was tobacco smokers. All the volunteers were subjected to estimate the blood pressure, lipid profile, biochemical and hematological parameters. The finding results showed that there was a significant increase (P<0.001) of systolic blood pressure in smokers when we compare to the control subjects. Also, the level of TC, TG, VLDL-c, LDL-c and Atherogenic index (AI) were highly significant raised (P<0.01), while the HDL-c level is significantly decreased (P<0.001) for smokers group compared to the controls one. However, the biochemical parameters didn’t change. The hematological results demonstrated that there was a significant decrease in RBC (p<0.01) and PLT (p<0.001) levels while a significant increase in MCV (p<0.05) level in smokers compared to the controls. Also, a significant raise in WBC (p<0.05) and Lym (p<0.001) levels were noticed in smokers group compered to controls one. As conclusion our study reveals that the tobacco consumption in cigarette form may be induce the sever alteration in lipid profile which cause the change in blood pressure that increase the cardiovascular risk for this population, Additionally, the cigarette smoke may be lead to remarkable change in blood constituents and appearance of inflammation status in the body.



Tobacco, Smokers, Lipid profile, Atherogenic index, Biochemical markers.


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