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Year : 2020, Volume : 13, Issue : 6
First page : ( 449) Last page : ( 454)
Print ISSN : 0974-4169. Online ISSN : 0974-4150. Published online : 2020  15.
Article DOI : 10.5958/0974-4150.2020.00080.2

Phenolic profile, Anti-inflammatory and Diuretic properties of Asplenium ceterach tested on Albino mice and Wistar albino rats

Sidhoum Rekia1, bey Mostapha Bachir2,*, Halli Latifa3, Yalaoui Othmane4, Belkadi Asma5

1Laboratoire de Biochimie Appliquée, Département des Sciences Alimentaires, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, 06000.

2Bejaia, Algérie Laboratoire de Biochimie Appliquée, Département des Sciences Alimentaires, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, 06000.

3Bejaia, Algérie Centre de recherche et de développement du groupe SAIDAL, Alger, Algérie

4Département physico-chimie, Laboratoires MERINAL Alger, Algérie Centre de recherche et de développement du groupe SAIDAL, Alger, Algérie.

5Département physico-chimie, Laboratoires MERINALAlger, Algérie.

*Corresponding Author E-mail: bachirbeymustapha@gmail.com

Received:  07  ,  2020; :  28  ,  2020; Accepted:  19  ,  2020.

Abstract

Asplenium ceterach is a fern used in traditional medicine against kidney stones and as a diuretic agent. Thus, we set as objective of this study is the determination of the phenolic profile as well as the study of anti-inflammatory and diuretic properties of Asplenium ceterach (Rustyback). Phenolic composition is achieved by Highperformance liquid chromatography, the anti-inflammatory activity is determined in albino mice, and the diuretic activity in Wistar albino rats. The results of phenolic profile show an overall concentration of 3926 μg/g DM of Asplenium ceterach, of which 3/4 are represented by chlorogenic acid. This plant is endowed with an interesting plantar anti-inflammatory property and a topical anti-inflammatory comparable to that of ibuprofen. Asplenium ceterach expresses an excellent diuretic activity significantly higher than of Furosemide. This study confirms the traditional use of the infusion of Asplenium ceterach as a powerful diuretic and an anti-inflammatory.

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Keywords

Rustyback, phenolic composition, chlorogenic acid, biological property, In vivo activity.

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