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Asian Journal of Research in Chemistry
Year : 2018, Volume : 11, Issue : 4
First page : ( 746) Last page : ( 750)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.
Article DOI : 10.5958/0974-4150.2018.00131.1

Study on the Synthesis, Structure and Antimicrobial activity of the new Mannich base and its Transition Metal Complexes Derived from Phthalimide

Balakrishnan A.1, Dr. Sankar A.2,*

1Assistant Professor, PG and Research Department of Chemistry, Govt Arts College, Dharmapuri, Tamilnadu, India

2Assistant Professor, PG and Research Department of Chemistry, Kandaswami Kandars College, P. Velur, Tamilnadu, India

*Corresponding Author E-mail: sankbala16@gmail.com

Online published on 24 October, 2018.

Abstract

Cyclic aromatic secondary amines, like phthalimides, and related compounds possess structural features, which makes them to exert potential biological activities and pharmaceutical applications. A new Mannich base has been synthesized from phthalimide and its transition metal complexes also were prepared. The Mannich base ligand was synthesized by using phthalimide, formaldehyde and piperidine. The ligand as well as the metal complexes were characterized by various physical methods. The structure of the synthesized compounds are confirmed by UV, IR, and 1H NMR spectroscopic techniques. The antimicrobial activity of the ligand and the complexes were examined using different bacteria by disc diffusion technique.

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Keywords

Mannich base, Phthalimide, transition metal complex, and antimicrobial study.

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