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Asian Journal of Research in Chemistry
Year : 2018, Volume : 11, Issue : 2
First page : ( 453) Last page : ( 458)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.
Article DOI : 10.5958/0974-4150.2018.00082.2

Synthesis and biological evaluation of coumarin acetamide derivatives

Momin Kalimoddin I.1, Suryawanshi Vikas B.2, Bondge Abhay S.3, Dawale Jairaj K.4,*

1Rajarshi Shahu College, Latur, Maharashtra-413512, India

2Department of Chemistry, KMC College, Khopoli, Maharashtra--410203, India

3Shivneri College, Shirur Anantpal, Dist. Latur, Maharashtra-413544, India

4Research Laboratory for Pure and Applied Chemistry, M. M. College, Nilanga, Dist. Latur, MH-413521, India

*Corresponding Author E-mail: amritkund_jk@rediffmail.com

Online published on 2 June, 2018.


An efficient route has been developed for the synthesis of coumarin derivatives by green process, the ecofriendly protocol allows the reaction condition smooth. The diverse scope of salicylaldehyde has shown and synthesized intermediates showed potent inhibition of Antimicrobial activity. The synthesized derivatives characterized well by using spectroscopic techniques NMR, mass and IR analysis. This protocol allows diverse modification as well synthesis of coumarin acetamide derivatives.



Coumarin, acetamide, biological activity, reflux, modifications, synthesis.


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