Synthesis and biological evaluation of coumarin acetamide derivatives Momin Kalimoddin I.1, Suryawanshi Vikas B.2, Bondge Abhay S.3, Dawale Jairaj K.4,* 1Rajarshi Shahu College, Latur, Maharashtra-413512, India 2Department of Chemistry, KMC College, Khopoli, Maharashtra--410203, India 3Shivneri College, Shirur Anantpal, Dist. Latur, Maharashtra-413544, India 4Research Laboratory for Pure and Applied Chemistry, M. M. College, Nilanga, Dist. Latur, MH-413521, India *Corresponding Author E-mail: amritkund_jk@rediffmail.com
Online published on 2 June, 2018. Abstract An efficient route has been developed for the synthesis of coumarin derivatives by green process, the ecofriendly protocol allows the reaction condition smooth. The diverse scope of salicylaldehyde has shown and synthesized intermediates showed potent inhibition of Antimicrobial activity. The synthesized derivatives characterized well by using spectroscopic techniques NMR, mass and IR analysis. This protocol allows diverse modification as well synthesis of coumarin acetamide derivatives. Top Keywords Coumarin, acetamide, biological activity, reflux, modifications, synthesis. Top |