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Asian Journal of Research in Chemistry
Year : 2018, Volume : 11, Issue : 2
First page : ( 432) Last page : ( 440)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.
Article DOI : 10.5958/0974-4150.2018.00079.2

Estimation of Antibacterial Efficacy in Alkaloids of Anogeissus rotundifolia an Indigenous Medicinal Plant against Some Pathogenic Micro-organisms

Dr. Singariya Premlata1,**, Dr. Mourya Krishan Kumar2,*, Prof. Kumar Padma1

1Laboratory of Tissue Culture and Secondary Metabolites, Department of Botany, University of Rajasthan, Jaipur-302004

2Animal Disease Diagnostic Laboratory, Rural Veterinary Polyclinic, Hingonia, Jaipur (Rajasthan)

*Corresponding Author E-mail: mourya07@gmail.com

**Email: premlatasingariya@gmail.com

Online published on 2 June, 2018.

Abstract

Estimation of Antibacterial efficacy in alkaloids of different parts (Root, Stem, Bark, Flower and Gum) of Anogeissus rotundifolia against some pathogenic micro-organisms (bacteria). Alkaloids extracts of all the parts of selected plant were found to possess strong antibacterial efficacy against these test pathogens, as revealed by Zone of Inhibition, Activity Index, Minimum inhibitory concentration, Minimum bactericidal concentration and Total activity of extracts against each sensitive test pathogens were also evaluated. All the pathogens were found to be sensitive against these alkaloid extracts. Alkaloid extract of the root and stem showed best activity against Bacillus subtilis (G+ve bacteria), ZOI (16.50±0.24 mm), AI (1.100), MIC (0.078 mg/ml) and MBC (0.157 mg/ml). Highest Total activity (456.410 ml/gm) of gum alkaloid was found against Bacillus subtilis. The findings of the present study suggested the exploration of alkaloid extracts of Anogeissus rotundifolia for future antimicrobial drugs.

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Keywords

Antimicrobial, Alkaloids, Anaegissus ruteundifoia, Zone of Inhibition, Activity Index, Minimum Inhibitory Concentration, Minimum Bactericidal Concentration and Total Activity.

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