Synthesis, Characterization and Antimicrobial Activity of Some new 1, 4 Diaryl-3-Methyl-6-Imino-4, 7-Dihydro-1, 3-Thiazino (5, 4-d) Pyrazoles Yadav A.K.1, Mehdi Mazhar2,*, Fatima Tasneem3 1Prasad Inst. of Technology, Jaunpur (U.P.) 2Asst. Prof., Chemistry Dept., Shia P G College, Lucknow (U.P.) 3Asst. Prof., Chemistry Dept., Dr. A.H.R. Shia Degree College, Jaunpur (U.P.) *Corresponding Author E-mail: drmazharmehdi@gmail.com
Online published on 2 June, 2018. Abstract Pyrazolones (1) react with aromatic aldehydes to give 1-aryl-3 methyl-4-arylidene pyrazol-5-ones(2).. The condensation of 4-arylidene-pyrazol-5-ones (2) with thiourea/N-phenyl thiourea in alcoholic KOH led to formation of the title compounds 1, 4-diaryl-3-methyl-6-imino-4, 7-dihydro-1, 3-thiazine (5, 4-d) pyrazoles (3). The title compounds have been screened for their antibacterial activity against S.aureus and E.coli. Top Keywords Synthesis, Characterization, Antimicrobial Activity, new Pyrazoles. Top |