Microneedle arrays: Advancements, applications and future prospects in pharmaceutical delivery Sarella Prakash Nathaniel Kumar*, Valluri Surekha, Vegi Srujala, Vendi Veera Kumari, Vipparthi Anil Kumar Department of Pharmaceutics, Aditya College of Pharmacy, ADB Road, Surampalem, Kakinada, 533437, Andhra Pradesh, India *Corresponding Author E-mail: sarellaprakash@acop.edu.in
Online published on 10 April, 2025. Abstract Microneedle arrays have emerged as a cutting-edge technology revolutionizing the field of pharmaceutical delivery. These micron-sized needles offer a minimally invasive and painless approach to administer drugs, vaccines, and various therapeutic agents through the skin, bypassing traditional routes of administration. This review article comprehensively explores the advancements, applications, and future prospects of microneedle arrays in pharmaceutical delivery. This review delves into the different types of microneedle arrays, including solid, hollow, dissolving, and coated microneedles, highlighting their unique properties and fabrication techniques. The discussion encompasses recent breakthroughs in microneedle design, such as biodegradable materials, smart responsive systems, and personalized arrays tailored to specific patient needs. Furthermore, this review addresses the challenges and safety considerations associated with microneedle usage, such as skin irritation and regulatory aspects. It analyzes ongoing research efforts aimed at optimizing design, functionality, and scalability for large-scale manufacturing. The future prospects of microneedle arrays in pharmaceutical delivery qwew also discussed. Anticipated advancements in the field, including personalized medicine, combination therapy, and disease monitoring through biosensing, offer promising avenues for transformative healthcare solutions. In conclusion, microneedle arrays represent a paradigm shift in pharmaceutical delivery, offering numerous advantages over traditional methods. As research and development continue, these micro-sized devices hold the potential to revolutionize the landscape of drug administration, leading to safer, more effective, and patient-centric healthcare practices. Top Keywords Microneedle arrays, Pharmaceutical delivery, Drug delivery technology, Minimally invasive administration, Transdermal drug delivery. Top |