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Asian Journal of Pharmacy and Technology
Year : 2021, Volume : 11, Issue : 1
First page : ( 48) Last page : ( 52)
Print ISSN : 2231-5705. Online ISSN : 2231-5713.
Article DOI : 10.5958/2231-5713.2021.00008.8

Developed a validated analytical procedure for estimation of ondansetron by uv-spectroscopy as api and in tablets

Meenu C.1, Pradeep K. Y.2, Praveen K.3,*

1School of Pharmaceutical Sciences, SGRR University, Patel Nagar, Dehradun-248001, Uttarakhand, India

2Department of Pharmacy, LLRM Medical College, Meerut, Uttar Pradesh, India

3Quantum School of Health Sciences, Quantum University, Mandawar, Roorkee-247167, Uttarakhand, India

*Corresponding Author E-mail: pkqa1981@gmail.com

Online published on 27 April, 2021.

Abstract

Pharmaceutical analysis and need of drug Analysis pharmaceutical analysis is an important part of pharmaceutical chemistry which involves the science of extraction. Analytical research and development is a process which assures quality attributes and quality control of the products. A modest specific, perfect and delicate Ultra Violet-Spectroscopyprocessdeveloped for the determination of Ondansetron in bulk as well as tablets. Ondansetron shows the maximum absorbance at wavelength 302nm. Ondansetron showed the linearity, range 04-24μg per ml for this procedure with Correlation Coeff. (R2) was 0.9991. The technique was found definite as no intervention was detected with excipients. The recovery studies confirmed the correctness of the anticipatedtechnique and outcome was found 99.32 with RSD ±0.66. The process was confirmed as per the ICH guidelines. The proposed analytical process is suggested for monotonous analysis of Ondansetron as API and in tablet unit dosage forms.

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Keywords

Validation, Ondansetron, Ethanol, Precision, Accuracy.

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