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Asian Journal of Pharmacy and Technology
Year : 2021, Volume : 11, Issue : 1
First page : ( 36) Last page : ( 40)
Print ISSN : 2231-5705. Online ISSN : 2231-5713.
Article DOI : 10.5958/2231-5713.2021.00006.4

Formulating, pharmacognostic and physicochemical insights of polyherbal vermifuge formulation

Mr. Khade Vishvajit M.1, Mr. Hegaje Sourabh S.1, Mr. Redkar Mayuresh R.2, Mr. Dhande Chetan G.3

1Tatyasaheb Kore College of Pharmacy, Warananagar, Maharashtra, India, 416113

2Yashwantrao Bhonsale College of Pharmacy, Sawantwadi, Maharashtra, India, 416510

3Shree Santkrupa College of Pharmacy, Ghogaon, Maharashtra, India, 415111

Online published on 27 April, 2021.

Abstract

The objective of present investigation was to prepare and standardize the churna from the plant materials i.e. Ginger, Garlic, Clove, Neem for anthelmintic activity. The Churna was prepared by taking plant materials, grinding it and was sieved from 80mesh size. The prepared fine powder was then used for testing and standardization. The physicochemical, phytochemical, flow property, TLC was determined. The in-vitro study was carried out on the earthworms for the effect of prepared churna to show the anthelmintic activity. Also the stability study was carried out. The raw material was prepared and authenticated. The churna was prepared by mixing all the ingredients in the fine form. The aqueous and methanol extract of prepared churna showed anthelmintic activity in dose - at 10, 20, and 40 mg/ml concentration for worms. It can be concluded that the active constituents responsible for anthelmintic activity present in the aqueous and methanol extract of prepared churna. The prepared churna is stable, safe, and effective against the helminths and can we used as an anthelmintic.

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Keywords

Churna, Anthelmintics, Helminthes, Vermifuge, In-vitro study.

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