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Asian Journal of Pharmaceutical Research
Year : 2019, Volume : 9, Issue : 3
First page : ( 190) Last page : ( 192)
Print ISSN : 2231-5683. Online ISSN : 2231-5691.
Article DOI : 10.5958/2231-5691.2019.00030.3

Review on Perflutren, A Diagnostic Drug that is intended to be used for contrast enhancement during the indicated Echocardiographic procedures

Jain Mayur S.*, Dr. Barhate Shashikant D.

Shree Sureshdada Jain Institute of Pharmaceutical Education And Research, Jammer

*Corresponding Author E-mail: mayurjain176@gmail.com

Online published on 31 December, 2019.


Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.1, 2





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