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Asian Journal of Pharmaceutical Research
Year : 2018, Volume : 8, Issue : 4
First page : ( 249) Last page : ( 254)
Print ISSN : 2231-5683. Online ISSN : 2231-5691.
Article DOI : 10.5958/2231-5691.2018.00043.6

Nipah Viral Infection: An Emergency Outbreak Situation

Devi G. Chinna, Kumar A. Eswar

University College of Pharmaceutical Sciences, Palamuru University, Mahabub Nagar-509001, Telangana, India

Corresponding Author E-mail:

Online published on 25 December, 2018.

Abstract

Nipah virus (NiV) infection is an emerging Zoonosis that causes severe disease in both animals and humans and first identified in Malaysia in 1998 and identified as the pigs were the intermediate hosts. In Bangladesh the human were infected due to consuming of date palm sap and by eating infected fruit bats in between 2001 to 2004, humans became infected with NiV as a result of consuming date palm sap that had been contaminated by infected fruit bats. Acute respiratory syndrome and fatal encephalitis, seizures and can progress to coma within 24 to 48 hours has been observed in human infected with Nipah virus. The incubation period (interval from infection to the onset of symptoms) is believed to range from 4 to 14 days. Enzyme-linked immunosorbent assay (ELISA) is the test to identify the disease. The vaccines are under pre clinical studies and need to launch a standard vaccine by taking the outbreak as a challenging situation and essentially controlling measures has been taken to control fatality.

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Keywords

Nipah virus, Zoonosis, ELISA, Vaccine, Paramyxovirus, Nosocomial transmission.

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