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Asian Journal of Pharmaceutical Research
Year : 2017, Volume : 7, Issue : 4
First page : ( 244) Last page : ( 246)
Print ISSN : 2231-5683. Online ISSN : 2231-5691.
Article DOI : 10.5958/2231-5691.2017.00038.7

Form Fill Seal Technology: A Brief Review

Mr. Gayakwad Bhushan P.*, Dr. Barhate Shashikant D., Mr. Jain Mayur S.

Shri. Sureshadada Jain Institutes of Pharmaceutical Education and Research, Jamner, Maharashtra (India)

*Corresponding Author E-mail: bhushangayakwad5@gmail.com

Online published on 2 June, 2018.


Form fill seal (FFS) technology is an automated computer operated technology, to prepare sterile products. Mostly it is applicable for I.V. infusion bottles. In this process all steps such as formation of container, filling of container with content and sealing of container are performed sequentially, consistently and automatically in a closed sterile chamber of machine. This technology reduces the contamination rate below 0.1%. The reason behind FFS technology is to reduce the contamination during production in a closed sterile chamber of a machine. Thus there should be no personnel intervention to reduce the chances of contamination during the manufacturing of sterile products. Again it gives more production in very low operational cost with high assurance of sterility.



Sterile, Moulds, Parison, Class 100 Area, I.V. Bottles.


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