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Asian Journal of Pharmaceutical Research
Year : 2014, Volume : 4, Issue : 1
First page : ( 39) Last page : ( 43)
Print ISSN : 2231-5683. Online ISSN : 2231-5691.

Bioinspired synthesis of silver nanoparticles using Euphorbia hirta leaf extracts and their antibacterial activity

Kumar S. Sathish1, Melchias G.1,*, Ravikumar P.2, Chandrasekar R.3, Kumaravel P.4

1Department of Botany, St. Joseph's College (Autonomous), Tiruchirappalli, Tamil Nadu, India

2Govt. Arts College (Autonomous), Coimbatore, Tamil Nadu, India

3Institute of Forest Genetics and Tree Breeding, Coimbatore, Tamil Nadu, India

4Department of Biotechnology, Vysya College, Salem, Tamil Nadu, India

*Corresponding Author E-mail: gmelchias@yahoo.in

Online published on 18 June, 2014.


Development of reliable green synthesis of silver nanoparticles by various plants and microorganisms has been reported in many research aspects. However, the probable of plants as natural materials for the synthesis of nanoparticles and their compatibility to biological systems is yet to be fully explored. In this study, we report a simple green method for the synthesis of silver nanoparticles using Euphorbia hirta (E. hirta) leaves extract as a reducing and stabilizing agent. After exposing the silver ions to E. hirta leaves extract, rapid reduction of silver ions is observed leading to the formation of silver nanoparticles in solution. The synthesized nanoparticles were characterized by using UV-visible spectroscopy, Fourier transform infrared spectroscopy (FTIR), Field emission Scanning Electron Microscopy (FESEM) and Particle size analysis. The synthesized silver nanoparticles show maximum zone of inhibition against Bacillus subtilis, Vibrio cholera and Salmonella typhi.



Silver nanoparticles, E. hirta, Antimicrobial activity.


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