Design, Synthesis and anti microbial, anti-inflammatory, Antitubercular activities of some 2,4,5-trisubstituted imidazole derivatives Kalkotwar R. S.1,*, Saudagar R. B.2 1Department of Pharmaceutical Sciences, Bhagwant University, Ajmer, Rajashthan, India 2Department of Pharmaceutical Chemistry, R.G. Sapkal College of Pharmacy, Nashik, M.S., India *Corresponding Author E-mail: rsk_55@rediffmail.com
Online published on 18 June, 2014. Abstract A Novel Series of Some 2,4,5-trisubstituted imidazole derivatives were prepared with the aim to get better antibacterial activity, antifungal activity, antitubercular and anti-inflammatory activity. The structures of synthesized compounds were supported by means of IR, 1H NMR. Title compounds were evaluated for antibacterial activity, antifungal activity, antitubercular and anti-inflammatory activities. Among the synthesized compounds some compounds found to possess all these activities. The QSAR study for anti-inflammatory activity shows good results. Top Keywords QSAR, Antibacterial, antifungal, anti-inflammatory activity. Top |