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Asian Journal of Pharmaceutical Research
Year : 2020, Volume : 10, Issue : 4
First page : ( 260) Last page : ( 262)
Print ISSN : 2231-5683. Online ISSN : 2231-5691.
Article DOI : 10.5958/2231-5691.2020.00045.3

Biochemical profiling of antifungal soap activity of betel leaf (Piper betle L.) extract and garlic oil by In vitro method

Shah Rutuja R1, Patil Poonam J2, Adnaik Pratibha R1, Adnaik Rahul S1

1Anandi Pharmacy College, Kalambe, Tarfe, Kale

2Gahlot Institute of Pharmacy, Koparkharne

Online published on 27 April, 2021.


The most common problem in now days is related to the fungal infection. Present work was focused on developing herbal antifungal soap as of commercially available soap shows few of side effects to sensitive skin and are much costly. Presently we have used Piper betel leaf commonly known as betel leaf (khau pan) and garlic oil. The traditional Indian ayurvedic document describes several of its medicinal properties including as an effective antifungal agent. The present study was conducted to evaluate the secondary metabolite that contributes to its antifungal activity. In present work we have formulated antifungal soap of garlic oil and betel leaf extract with synergistic effect for the fungal infection. The different batches were formulated to study soap base effect in formulation and optimized batch was further used for herbal soap formulation. The formulation was evaluated and observed clear, good ability. The formulation of F3 batch shows best result of evaluation parameters as compare to F1 and F2. The optimized batch formulation of F3 showed good result. Microbial study has been done using microorganism such as Proteus vulgaris, bacillus, klebsiella pneumoniae, Staphylococcus aureus, pseudomonas aeruginosa, for measuring the effectiveness of an antimicrobial agent against fungi/bacteria grown in culture, the microorganism of the interest was swabbed uniformly across a culture plate. Then soap of 5X5 mm was placed on the surface of the agar. Then the plates were placed in the incubator for 24 hrs.



Antifungal, Herbal Soap, Betel Leaf, Garlic Oil.


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