Determination and Development of UV-Spectrophotometric method for the Amodiquine Hydrochloride by using quality by design (QBD) approach Ashok Patil Karishma1, Dinkar Firke Sandip2,* 1Research Scholar, R. C. Patel Institute of Pharmaceutical Education and Research, Shipur, Dhule (425405) 2Professor, Pharmaceutical Chemistry Department, R. C. Patel Institute of Pharmaceutical Education and Research, Shipur, Dhule (425405) *Corresponding Author E-mail: sandipfirke@rediffmail.com
Online published on 31 December, 2019. Abstract To develop a simple, accurate, and inexpensive UV sepectrometric method for the determination of the Amodiquine hydrochloride by using quality by design (QbD) approach. The double beam spectrophotometer of Shimadzu UV-1800 by using a determination of UV spectrophotometer method. The amodiquine Hydrochloride is soluble with Distilled Water & methanol (9: 1) as solvent and wavelength of 341 nm was selected as of 0.998. The (LOD) and (LOQ) were amodiquine Hydrochloride recovery was found to be 99.6%. Top Keywords Quality by design, Amodiquine hydrochloride estimation, Spectrophotometric estimation. Top |